Rochester, Minn.: Mayo Foundation for Medical Education and Research; 2018. Int J Tuberc Lung Dis. Philadelphia, Pa.: Saunders Elsevier; 2016. https://www.clinicalkey.com.  |  Accessed April 2, 2019. Peripheral neuropathy, a result of damage to the nerves outside of the brain and spinal cord (peripheral nerves), often causes weakness, numbness and pain, usually in your hands and feet. National Center for Biotechnology Information, Unable to load your collection due to an error, Unable to load your delegates due to an error. Early diagnosis and treatment offer the best chance for controlling your symptoms and preventing further damage to your peripheral nerves. The Foundation for Peripheral Neuropathy. This site complies with the HONcode standard for trustworthy health information: verify here. Accessed March 26, 2019. Peripheral neuropathy fact sheet. Int J Tuberc Lung Dis. It can also affect other areas of your body. https://www.uptodate.com/contents/search. Any use of this site constitutes your agreement to the Terms and Conditions and Privacy Policy linked below. Methods: Seek medical care right away if you notice unusual tingling, weakness or pain in your hands or feet. Clipboard, Search History, and several other advanced features are temporarily unavailable. In: Goldman-Cecil Medicine. https://www.foundationforpn.org/what-is-peripheral-neuropathy/evaluation-and-tests/. Accessed March 25, 2019. NLM Hypothyroidism: Can it cause peripheral neuropathy? Philadelphia, Pa.: Elsevier; 2018. https://www.clinicalkey.com. Peripheral neuropathy can result from traumatic injuries, infections, metabolic problems, inherited causes and exposure to toxins. Peripheral neuropathy risk factors include: Complications of peripheral neuropathy can include: The best way to prevent peripheral neuropathy is to manage medical conditions that put you at risk, such as diabetes, alcoholism or rheumatoid arthritis. Median time to presentation from initiation of MDR-TB therapy was 9.1 months. Ten (13%) of these patients presented with symptoms of peripheral neuropathy, confirmed by electromyography. Antimicrob Agents Chemother. Peripheral neuropathy treatments. Safety implications of combined antiretroviral and anti-tuberculosis drugs. Treatment of diabetic neuropathy. Get the latest research from NIH: https://www.nih.gov/coronavirus. This site needs JavaScript to work properly. Results: Chavez Pachas AM, Blank R, Smith Fawzi MC, Bayona J, Becerra MC, Mitnick CD. See how we're providing safe in-person care and virtual visits, Review the latest COVID-19 resources and research advancements, Mayo Clinic College of Medicine and Science, Mayo Clinic Graduate School of Biomedical Sciences, Mayo Clinic School of Continuous Professional Development, Mayo Clinic School of Graduate Medical Education, See our safety precautions in response to COVID-19. Neurological examinations. Accessed March 27, 2019. The usual dose of pyridoxine PO for prophylaxis is: What is peripheral neuropathy. Peripheral neuropathy refers to damage to the nerves located outside of the central nervous system. Sensory nerves that receive sensation, such as temperature, pain, vibration or touch, from the skin, Motor nerves that control muscle movement, Autonomic nerves that control functions such as blood pressure, heart rate, digestion and bladder, Gradual onset of numbness, prickling or tingling in your feet or hands, which can spread upward into your legs and arms, Sharp, jabbing, throbbing or burning pain, Pain during activities that shouldn't cause pain, such as pain in your feet when putting weight on them or when they're under a blanket, Feeling as if you're wearing gloves or socks when you're not, Excessive sweating or not being able to sweat, Changes in blood pressure, causing dizziness or lightheadedness, Diabetes, especially if your sugar levels are poorly controlled, Vitamin deficiencies, particularly B vitamins, Infections, such as Lyme disease, shingles, Epstein-Barr virus, hepatitis B and C, and, Autoimmune diseases, such as rheumatoid arthritis and lupus, in which your immune system attacks your own tissues, Repetitive motion, such as those performed for certain jobs.