MUM1 is a gene primarily identified in Multiple Myeloma cell line where it was localized in region of chromosomal translocations t(6;14)(p25;q32) placing this gene in proximity of IgH enhancer locus. 10. cell lines with MUM1 gene mutations from the Klijn et al., Nat. Mod Pathol 2003; 16: 802–810. MUM-1, cell lines with high or low expression of MUM1 gene relative to other cell lines from the Klijn et al., Nat. Tumours and proliferations of other than lymphocytic and melanocytic lineages are negative.
Nature: Nuclear transcription factor necessary for development and activation of B lymphocytes. tissue samples with high or low expression of MUM1 gene relative to other tissue samples from the HPA Tissue Sample Gene Expression Profiles dataset. interacting proteins for MUM1 from the Pathway Commons Protein-Protein Interactions dataset. microRNAs regulating expression of MUM1 gene predicted using nonconserved miRNA seed sequences from the TargetScan Predicted Nonconserved microRNA Targets dataset. B-cell lymphoma: low grade (I/II) of follicular lymphoma (10%), primary cutaneous DLBCL, leg type. Rank scores of expression calls are normalized across genes, conditions and species. Myotubularin is thought to be involved in the development and maintenance of muscle cells. Colon is recommended as negative tissue control. PubMedIDs of publications reporting gene signatures containing MUM1 from the GeneSigDB Published Gene Signatures dataset. small molecule perturbations changing expression of MUM1 gene from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset. cell lines with high or low copy number of MUM1 gene relative to other cell lines from the CCLE Cell Line Gene CNV Profiles dataset. 2006; 130: 1819-24. tissues with high or low expression of MUM1 gene relative to other tissues from the Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles dataset. Natkunam Y, et al. cell lines with high or low expression of MUM1 gene relative to other cell lines from the BioGPS Cell Line Gene Expression Profiles dataset. Mod Pathol 2001; 14:686-94, 3 Carbone A, Gloghini A, Aldinucci D, et al. 1 Petitjean, B., Jardin, F., Joly, B., Martin-Garcia, N., Tilly, H., Picquenot, J.M., Briere, J., Danel, C., Mehaut, S., Abd-Al-Samad, I., Copie-Bergman, C., Delfau-Larue, M.H. Rouse RV, Natkunam Y. transcription factors regulating expression of MUM1 gene predicted using known transcription factor binding site motifs from the MotifMap Predicted Transcription Factor Targets dataset. 2006; 24:4135-42. Graph generated 30 August 2019 using data from, Tag cloud generated 30 August, 2019 using data from, Creative Commons Attribution-ShareAlike 4.0 International License, PWWP3A; PWWP domain containing 3A, DNA repair factor, PWWP domain-containing DNA repair factor 3A. tissue samples with high or low expression of MUM1 gene relative to other tissue samples from the GTEx Tissue Sample Gene Expression Profiles dataset. 2000; 95:2084-92.
histone modification site profiles with high histone modification abundance at MUM1 gene from the ENCODE Histone Modification Site Profiles dataset. Multiple Myeloma Oncogene 1 (MUM-1) - IHC Primary Antibodies It appears that your browser has JavaScript disabled. Tonsil is recommendable as positive tissue control, where the late stage germinal centre B-cells must display a moderate to strong distinct nuclear staining. gene perturbations changing expression of MUM1 gene from the GEO Signatures of Differentially Expressed Genes for Gene Perturbations dataset.